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Lipid appears to accumulate among the acyl chains on the lipid bilayer of the ER membrane

Furthermore, these low-resolution techniques were used long before the scientific community fully accepted the concept of biologically active proteins lacking a fixed 3D structure, and were instrumental in laying the groundwork for this vital discovery, played a crucial role in the discovery of the protein intrinsic disorder phenomenon and, later, offered tremendous help with establishing the IDP/IDR field

Howell MD, Wollenberg A, Gallo RL, et al

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