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Sterile water, lacking a preservative, is better suited for single-use scenarios or procedures where the absence of additives is preferred, such as in sensitive patients or irrigation tasks

(3) For a biosimilar biological product (as defined in 414.902) (i) In circumstances in which negative or zero manufacturer's ASP data is reported for one or more, but not all, NDCs for a given quarter, the payment limit for the given quarter is calculated using only NDCs with positive manufacturer's ASP data

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Levels of methylmalonic acid (MMA) and homocysteine rise, because the body needs B12 to convert them into other compounds