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NNMT inhibition as a therapeutic strategy has been explored in industry pharmaceutical pipelines (including a Pfizer program for non-alcoholic fatty liver disease that was reportedly discontinued in early clinical development), but no NNMT inhibitor has reached regulatory approval to date

The scale may not move dramatically even as patients see visible changes in the mirror and clothing fit

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Vitamin B12 is a water-soluble vitamin essential for energy metabolism, red blood cell formation, and neurological function, but has no licensed indication for weight loss in the UK