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Berg and Shaw presented a cascade-testing algorithm that stratified patients first by total serum vitamin B 12 levels and second by MMA levels, using cutoffs of 118 pmol/L and 0.80 mol/L, respectively (Berg and Shaw, 2013)

A molecular perspective on age-dependent changes to the heat shock axis

Multicomponent exercise not only improves physical fitnessincluding scores on the Short Physical Performance Battery (SPPB), a popular scale for measuring frailtybut also improves cognitive function after 24 months of exercise in older patients with diabetes and impaired lower-limb function [235]

Richa R, Yadawa AK, Chaturvedi CM (2017) Hyperglycemia and high nitric oxide level induced oxidative stress in the brain and molecular alteration in the neurons and glial cells of laboratory mouse, Mus musculus