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0:00 - Introductions: Reconnecting with Katie Emerson at Expo West 2025 The episode opens with Mike and Ben welcoming Katie Emerson back to the podcast after roughly 18 months

doi: 10.1160/TH12-04-0275 [DOI] [PubMed] [Google Scholar] 44

doi: 10.1038/s41575-023-00822-y

An increasing body of evidence suggests that disturbances in the pulmonary mechanical microenvironment, a complex interplay of extracellular matrix (ECM) stiffness, alveolar surface tension, cellular forces, and cell-matrix interactions, play a crucial role in the pathogenesis and progression of these diseases ( Owing to their unique size and highly tunable physicochemical properties, nanomaterials present unparalleled opportunities to finely adjust the pathological microenvironment within the lungs ( Here, we explore how nanomaterials can address dysregulation in the lungs mechanical microenvironment by modulating ECM properties, normalizing alveolar surface tension, and influencing mechanotransduction pathways in pertinent lung cells