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1.2.5 Sex-biased differences in T cell exhaustion trajectories and therapeutic responses There are gender differences in the efficacy of immunotherapy and the incidence of autoimmune toxicity observed across different cancer types, for example, men have higher rates of objective response to PD-1/PD-L1 inhibitors in certain tumors, while women tend to experience more severe immune-related adverse events (72)

Another aerosol research spray, supplied in solution with no reconstitution required

Methods Material availability All unique reagents generated in this study are available from the corresponding author under a completed Materials Transfer Agreement

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