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In: Goldman L, Schafer A, eds

2024;22(7):e8883

Therefore, while the mentioned diseases are those that require cortisone treatment, medical supervision is essential regarding at which stage of treatment cortisone should be taken, for how long, and in what manner

Specifically, Cyp51a1 expression is decreased in SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 (SMARCA4) and E2F transcription factor 1/2/3 ( E2f1/2/3 ) knockout mice, while increased in tudor domain containing 7 ( Tdrd7 ), KLF transcription factor 4 ( Klf4 ), MAF BZIP transcription factor G ( Mafg ), and Mafk knockout models, further supporting its role in lens development and cataractogenesis [47]