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Description

It also boosts energy, helping to increase activity levels, which is often a concern for many patients

For context on SAMe and related evidence limits, see the NIH NCCIH resource S-Adenosyl-L-Methionine (SAMe): In Depth

This means you cant just buy them over the counter like you would a packet of paracetamol

Supplementation with trimethylglycine (betaine) at 12g daily or SAMe (S-adenosylmethionine) at 400800mg daily can offset potential methyl donor depletion