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Effect of diphenyleneiodonium chloride on intracellular reactive oxygen species metabolism with emphasis on NADPH oxidase and mitochondria in two therapeutically relevant human cell types

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25 Induction of remission using 5-ASAs usually requires doses of 4 to 4.8 g of oral mesalazine or equivalent, with daily dosing shown to be as effective as split day dosing, while resulting in improved adherence