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Instead, our data (Fig

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19 Iron containing proteins are also involved in a number of other cellular processes including xenobiotic transformation, the excretion of organic compounds, nucleic acid replication and repair, and cellular signaling

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This deactivation of MKPs allows for the unimpeded progression and sustained activation of the pro-inflammatory ERK1/2, JNK, and p38 signaling cascade within the MAPK pathway (Son et al., 2011)

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Recently, choline has emerged as a promising possible modifier of the genomic sequence that modulates gene expression by affecting the concentration of SAM, which is the main cellular methyl donor molecule participating in epigenetic mechanisms such as DNA and histone methylation [21]

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