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Recent Updates In April 2023, the Melvin and Bren Simon Comprehensive Cancer Centre at Indiana University became the principal site for providing first-in-human clinical trials providing first-in-human clinical trials for patients with relapsed multiple myeloma

Long-Term Medication Users Medications such as metformin (used for diabetes) and proton pump inhibitors (used for acid reflux) can interfere with B12 absorption when taken long term, making supplementation necessary

As a result, the safe upper intake level of riboflavin has not been established

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