glutathione persister cells

glutathione persister cells peroxidase 4‐dependent glutathione high‐consumption drives acquired platinum chemoresistance in lung cancer‐derived brain metastasis - Liu - 2021 - Clinical and Translational Medicine Frontiers | Drug-tolerant persister cells:

Name: glutathione persister cells peroxidase 4‐dependent glutathione high‐consumption drives acquired platinum chemoresistance in lung cancer‐derived brain metastasis - Liu - 2021 - Clinical and Translational Medicine Frontiers | Drug-tolerant persister cells:
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Frontiers Drug tolerant persister cells: the deadly survivors in hematological malignancies The cell biology of ferroptosis PMC glutathione persister cell Role of in Cancer: From Mechanisms to Therapies Drug induced tolerant persisters in tumor Drug tolerant persister cancer cells are vulnerable to GPX4 inhibition Nature

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10.1186/s13287-022-02831-1 38 PossematoR.MarksK

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Estimates of dosing rate and average steady-state concentrations, which may be calculated using clearance, are independent of any specific pharmacokinetic model

Therefore, understanding the biological properties of PPs after their metabolism and tissue intake in the body can supposedly help to identify the exact behavior of these metabolites in AFs therapy scenarios