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The localization of HPV18 E2 within the mitochondrial membrane leads to morphological changes of cristae, resulting in an amplified release of ROS from mitochondria

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Mutations in SCO2 are associated with a distinct form of hypertrophic cardiomyopathy and cytochrome c oxidase deficiency

TXNIP activation appears to be essential for NLRP3 assembling by different inflammasome agonists, such as monosodium urate crystals (MSU), ATP or high concentration of glucose (152)