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Mechanistically, chromatin immunoprecipitation (ChIP) and dual luciferase reporter gene assays were used to confirm that signal transducer and activator of transcription 3 (STAT3) binds to the GPX4 promoter region and promotes its transcription, whereas TST blocked GPX4 expression by regulating STAT3
It is also found in various foods , especially in certain vegetables , fruits particularly asparagus, spinach, avocados, peaches, and apples -and in meat
10.1016/j.exer.2018.08.019 33 UrsiniF.MaiorinoM
Activated eosinophils form more of the functional NADPH oxidase complex and produce more superoxide than neutrophils or macrophages.98 Secretory phospholipase A2 is mainly located in specific granules in the eosinophil and copurifies with ECP in granule fractions
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