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Curr Med Sci

As with many medications, ongoing research is needed to fully understand the long-term implications of its use

Westphal, J

One of the more commonly used methods to induce disc degeneration in recent studies has been the needle puncture injury method in both in vivo and ex vivo small and large animal models, where the IVD is punctured using needles of various gauges (Korecki et al., 2008