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Additionally, ChaC1, by stimulating the GCN2/eIF2/ATF4 pathway, enhances necroptosis induced by cystine deprivation (54)

Prezentare: Glutationul este o tripeptid fiziologic care este implicat n mai multe procese biologice i joac un rol important n reaciile de detoxifiere, protejnd celulele de efectele nocive ale oxidanilor xenobiotici, de mediu i intracelulari (radicali liberi, intermediari oxigen reactivi) i de radiaii

Subsequently, we used Fishers exact test to determine the significance of the enrichment of shared tier-1 targets among the genes associated with each subsystem