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doi: 10.1016/J.BBAMCR.2014.04.017 56 KawiakAKosteckaA

This mechanism has particularly important implications for wound healing research

Control glucose Effective management of blood glucose levels and enhancement of glucose metabolism are crucial for delaying the progression and improving the prognosis of DKD [68]

Activation of SIRT1 has been shown to boost the expression of antioxidant genes by deacetylating and activating Nrf2, subsequently mitigates cell damage caused by oxidative stress and dysregulated iron metabolism