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It is important to note that exact dosing schedules varied between trial cohorts and protocols

Remarkably, ER-, but not ER-specific ligands, lead to increased phosphorylation of ERK 1/2, which initiates cell cycle entry (demonstrated by the up-regulation of mitotic markers such as CDK1/cdc2 and PCNA), DNA replication, and duplication of the centrosome -the major microtubule-organizing center in the cell- in dividing cells (Wang et al., 2008)

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This survey collected data on the monthly per capita consumer expenditure, along with household food purchases of 223 food items, for a 30-day recall period (23)