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Follow-up Repeat metabolic markers after 4-12 weeks, with closer review during dose escalation or major appetite changes

Increase weights when you exceed the target rep range, and adjust calories if progress stalls

Figure 1 The decreased levels of insulin, and increased levels of glucagon activates the hormone-sensitive lipase (HSL) involved in lipolysis and secretes non-esterified fatty acids (NEFAs) from fat cells ( -oxidation takes place in the mitochondria creating acetyl-CoA

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