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For those with autoimmune disorders , stimulating the immune system might not always be advisable

While traditionally viewed as a stable lineage committed to immunosuppression, emerging evidence indicates that certain Treg subsets can acquire effector-like characteristics under inflammatory conditions, including the production of pro-inflammatory cytokines

However, including seropositive individuals in phase II and III trials should be promoted to ensure population-wide implementation of the vaccine after registration

In these instances, naturopathic treatments can work alongside medical interventions to enhance overall well-being and tackle the root causes of symptoms to work towards full remission of PANS symptoms