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After completing a treatment cycle, taking 2 to 4 weeks off before potentially repeating allows assessment of maintained improvements

J Med Chem 55(24):1101311021 Song H, Montesdeoca N, Efanova E, Li X, Karges J, Xiao H, Shang K, Zhang H (2025) A cGAS-STING pathway activating cobalt (III) cyclam prodrug for combined chemotherapy and immunotherapy of breast cancer

[DOI] [Google Scholar] 22.Frenkel E.P., White J.D., Reisch J.S., Sheehan R.G

This binding enhances the activity of GTPase Drp1, resulting in mitochondrial fusion and fission imbalances, mitochondrial distribution abnormalities, and mitochondrial axonal transport defects