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CRC Press, Boca Raton, FL, pp 1530 Brezova V, Valko M, Breza M et al (2003a) Role of radicals and singlet oxygen in photoactivated DNA cleavage by the anticancer drug camptothecin: an electron paramagnetic resonance study

While it offers many effects, it is popularly known as the "Shiratama (White Jewel) Injection" particularly for its skin brightening properties

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Treatment of fibroblasts from COPD patients with hemin to activate HO-1 results in reduced cellular senescence, improved mitochondrial function, and reduced ROS production [122] Since Nrf2 activates many other antioxidant genes in addition to HO-1, this suggests that activators of Nrf2 and inhibitors of Keap1 might be even more effective against oxidative stress in COPD