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Abstract Sepsis is a systemic immune-metabolic disorder syndrome caused by infection, in which gut microbiota dysbiosis plays a central role in the occurrence and development of multi-organ dysfunction

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10.1248/bpb.b18-00855 61 MiyakeT.NakamuraS.ZhaoM.SoK.InoueK.NumataT.et al (2016)

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There exists an imperative for additional rigorously designed clinical trials and standardized formulations to substantiate efficacy, ascertain safety, and delineate optimal dosing protocols