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Deters, M., Klabunde, T., Kirchner, G., Resch, K

mTOR is a key player in pathways that control cell growth

Similarly, in a liver ischemiareperfusion model, mTOR-deficient mice or those treated with rapamycin displayed greater histopathological damage, elevated alanine transaminase and lactate dehydrogenase levels, and increased caspase-3 activation and NF-B translocation [37]

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