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But still, both excess and deficiency of essential trace elements are ascribed to adverse pregnancy outcomes along with infertility in women (Reference Skalnaya, Tinkov and Lobanova80) (Table 1)

In colitis and EAE mice, the anti-inflammatory effects were connected to the direct targeting of the aryl hydrocarbon receptor (AhR) and modulating the signaling pathways contributing to the inhibition of Th17 differentiation and the activation of dendritic cells and to a reduction in the inflammation barrier functions, respectively [38,40]

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Specifically, the association between intestinal disorders and PD pathogenesis attracting many researchers' attention may be due to the existence of the gut-brain axis