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The 54 genes whose expression was reversed by GHK included node molecules YWHAB, MAP3K5, LMNA, APP, GNAQ, F3, NFATC2, and TGM2, all of which are involved in regulation of multiple biological functions through a complex molecular network [20]

Whole-body cryotherapy chambers operate below minus 110 degrees Celsius but for much shorter durations (2-3 minutes versus 10-15 minutes for water immersion)