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In ACLY -knockout cell lines, the addition of exogenous acetate at physiological blood concentrations sustained acetyl-CoA levels and lipogenic metabolites via ACSS2 induction, suggesting that circulating acetate is likely adequate for compensatory lipid synthesis 80,105

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[DOI] [PubMed] [Google Scholar] 85.Huang YC, Chang HH, Huang SC, Cheng CH, et al

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