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The oxidative stress produced in VSMC in diabetes may shift them from a contractile to a proliferative phenotype, thus further inhibiting vasodilation and enhancing lesion formation

Traffic 10: 364371 Killian JK, Kim SY, Miettinen M, Smith C, Merino M, Tsokos M, Quezado M, Smith WI Jr, Jahromi MS, Xekouki P, Szarek E, Walker RL, Lasota J, Raffeld M, Klotzle B, Wang Z, Jones L, Zhu Y, Wang Y, Waterfall JJ et al (2013) Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor

Effects observed were very similar to those induced during a local graft-versus-host reaction in the popliteal lymph node assay (de Bakker et al., 1990)

The following incidences of primary carnitine deficiency in newborns have been reported: 1:40,000 in Japan [70], 1:37,0001:100,000 in Australia [71], 1:105,000 in Portugal [72], 1:142,000 in the USA [73], 1:250,000 in Germany [74] and 1:297 in the Faroe islands [68]