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These signaling systems of the glutamatergic system have been found to be altered in preclinical models of neurological disorders

Fibrosis: Sustained signaling drives fibroblast activation and extracellular matrix deposition Bone disorders: Impaired signaling alters bone remodeling and density, contributing to osteoporosis

Supplementation with lipoic acid may offer complementary nerve-health benefits

He believes this could help us understand the broader question of why cells in the body deteriorate or age at different rates to others, why some individual cells are more resilient to stress, or even why some people die earlier than others