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Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift

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Statistical Analyses Data are expressed as means SEM

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Considering the clinical evidence collected over the years (and discussed above), the 2023 GOLD Report confirmed that NAC and S-CMC may reduce exacerbations in COPD patients not receiving ICS, whereas erdosteine has been shown to have a significant effect on exacerbations irrespective of the concurrent treatment with ICS [29]

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