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This apparent discrepancy is not uncommon for this type of compound as similar results have been previously reported for ellagic acid, which displays 100 fold higher potency against parasites than against the purified GST enzyme, with a Ki of 74 M in an enzyme assay but an EC 50 of 0.8 M in antiparasitic assays (Sturm et al., 2009)

As SERF2 and TERRA rG4 both in isolation are shown to promote amyloid formation 47,106 , we speculate that under unfavorable conditions like stress, their relatively strong interactions could suppress their ability to bind and promote aggregation of amyloid substrates, a phenomenon we demonstrated for the SERF2 homologous protein Znf706 27

Complete cognitive baseline testing and health screening to establish metrics for tracking improvement and protocol optimization