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In summary, future studies will deepen our understanding of ferroptosis, thereby providing new perspectives for combating neurodegeneration and brain aging in AD

Zhang, L., Lu, Q

Positive regulators of ferroptosis inhibit CRPC progression Inducing ferroptosis by critical down-regulation of SLC7A11 and GPX4 expression slows the growth of PCa

meningitidis (Exley et al., 2005), which metabolizes the lactate by at least three lactate dehydrogenases: two membrane-bound flavin mononucleotide-containing lactate dehydrogenases, LldD and LdhD, which catalyze the oxidation of L -lactate and D -lactate, respectively, and a soluble NAD + -dependent D -lactate dehydrogenase, LdhA (Erwin and Gotschlich, 1993, Erwin and Gotschlich, 1996