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This approach utilized 21 human cellular systems, including 2D and 3D in vitro models of vital organs (such as liver, heart, kidney, and lung), co-cultured with allogeneic peripheral blood mononuclear cells to identify potential off-target toxicity and a whole blood assay for cytokine release risk assessment

J., Clarke, R., Ueland, P

SELENOP expression considerably overlapped with that in glial fibrillary acidic protein-positive astrocytes and was generally more prominent in white matter