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Important environmental provocation factors in atopic eczema (adapted from Ring et al., 1996) Unspecific provocation factors: Irritants Microbial skin colonization or infection e.g., Staphylococcus aureus Pityrosporum ovale Herpes simplex (Eczema herpeticum) Psychological stress, emotional factors Specific provocation factors (individual hypersensitivity): IgE-mediated allergy e.g., Food House dust mite Animal dander Pollen Microbial colonisation

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72 More serious reactions are rare, but you should seek immediate medical attention if you develop hives, swelling of the lips, throat, or tongue, or difficulty breathing

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