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Clinical trials of TFEB activators such as trehalose (NCT05136885 and NCT05597436) and PPAR agonists such as gemfibrozil (NCT02045056) further illustrate the challenges of translating preclinical findings into clinical benefits

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The standard bacteriostatic water reconstitution generally works well without pH adjustment, but researchers working with very long reconstitution-to-use timelines (approaching the 28-day limit) may benefit from knowing that lower pH within the acceptable range tends to preserve potency better

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