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Meanwhile, in non-selenium containing Gpxs, which represent the majority of non-vertebrate Gpxs, the selenocysteine residue at the active site is replaced by a cysteine residue and the enzyme follows Michaelis Menten saturation kinetics (Toppo et al., 2009)

225.Kumano K, Arai S, Hosoi M, Taoka K, Takayama N, Otsu M, et al

470 Upadacitinib is another oral Janus kinase inhibitor that plays a role in the treatment of UC by suppressing the JAK signaling pathway, thereby reducing the inflammatory response