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Cerebrospinal fluid samples from ASD children should be useful to gain better insight into the potential etiological role of oxidative stress in ASD, although it is difficult to obtain cerebrospinal fluid samples from children

30 In vivo studies in lymphocytic choriomeningitis virus-infected mice have shown that mTORC2 prevents ferroptosis in virus-specific memory CD4 T cells by limiting lipid peroxidation and mitochondrial ROS accumulation, primarily through activation of AKT and inhibition of GSK3, thereby supporting their long-term survival