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Fer-1 has also been found to inhibit ROS/RNS, attenuating rotenone-induced -synuclein aggregation in dopaminergic SH-SY5Y cells (Kabiraj et al., 2015), thereby reversing MPTP-triggered behavioral deficits in a mouse model of PD and protecting the neurons ( 3.2 Alzheimers disease Alzheimers disease (AD) is marked by the gradual deterioration of neurons within the CNS