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According to the manufacturer the kinases possess the following substrate specificities: adenosine kinase (AK, NK14), guanylate kinase (GMPK, NMPK21) and adenylate kinase (AMPK, NMPK23) convert purine nucleoside/nucleotide substrates, while uridine monophosphate-cytidine monophosphate kinase (UMP-CMPK, NMPK22) and nucleoside diphosphate kinase (NDPK, NDPK32) accept both purine and pyrimidine nucleoside/nucleotide substrates

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