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B12 is obtained exclusively from animal-derived foods (meat, fish, dairy, eggs) or fortified products, making vegans and vegetarians particularly vulnerable to deficiency

In univariate analysis SHUNT% was the strongest single predictor of new clinical decompensation, liver-related death, or liver transplantation (n=13 with clinical outcomes, AUROC 0.886 for V1.1, 0.853 for V2.0, and 0.834 for LDT 1.0) with no significant differences in operating characteristics between Test versions

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Facchini FS, Hua N, Abbasi F, Reaven GM: Insulin resistance as a predictor of age-related diseases