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The existing antidepressant drugs mainly target the dysfunctions of various neurotransmitters, while the efficacy of antidepressant therapeutics is undermined by different adverse side-effects

The same authors have shown that TxnRd2 is also able to control mitochondrial H 2 O 2 levels after a high-fat, high-sucrose diet in the heart but not in skeletal muscle

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These signals are decoded by sensors such as calmodulins, CBL-CIPK complexes, and CDPKs, which relay information to kinase-dependent cascades, including the SOS pathway in Arabidopsis thaliana , essential for ionic homeostasis under salinity (Ma et al