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Tailored treatment strategies in first line therapy for ovarian cancer patients: a critical review of the literature

These tools analyze amino acid sequences to identify cysteine residues that are likely to undergo S-glutathionylation

Ovarian tumours epigenetically reprogram resident MSCs toward a partial mesenchymal-to-epithelial transition controlled by WT1/EZH2, enabling tight CA-MSCcancer cell binding and co-metastasis. Pharmacological EZH2 inhibition attenuated this metastatic escort function, yet did not abolish it, indicating that even modified MSCs remain metastasis-competent [199]

Neurocognitive and Organ-Function Models: Ongoing studies examine whether modulating IGF-1like activity can influence trajectories of neurological changes, muscle atrophy, and organ function in aging or disease models, always under controlled research conditions