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Description

It can lead to neuropathy, megaloblastic anemia, and pernicious anemia, [2] [13] causing symptoms including fatigue, paresthesia, depression, cognitive decline, ataxia, and even irreversible nerve damage

Aminoglutethimide and testolactone (Teslac) were the first generation of non-selective irreversible AIs

doi: 10.3389/fnins.2012.00182

FTL004, an anti-CD38 mAb with negligible RBC binding and enhanced pro-apoptotic activity, is a novel candidate for treatments of multiple myeloma and non-Hodgkin lymphoma