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Int Urogynecol J 34:22072216 Cho SY, Jeong SJ, Lee S, Kim J, Lee SH, Choo MS, Oh SJ (2021) Mirabegron for treatment of overactive bladder symptoms in patients with Parkinsons disease: a double-blind, randomized placebo-controlled trial (Parkinsons Disease Overactive bladder Mirabegron, PaDoMi Study)

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This suggests that Fragment 176-191 may influence signaling pathways or transcription factors that enhance the production of beta-3 adrenergic receptor mRNA, leading to increased synthesis of the beta-3 adrenergic receptors protein