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Bogaert E, Van Damme P et al (2006) Vascular endothelial growth factor in amyotrophic lateral sclerosis and other neurodegenerative diseases

As mentioned earlier, it plays a crucial role in red blood cell production, DNA synthesis, and nerve cell maintenance

It typically begins with declining blood levels (stage I), followed by low cellular levels (stage II), increased homocysteine levels and reduced DNA synthesis (stage III), and finally macrocytic anemia (stage IV)