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About this article Cite this article Stellingwerff, T., Peeling, P., Garvican-Lewis, L.A

Conditional Amino Acids Conditional amino acids are usually produced by the body, but during certain conditions such as illness, stress, injury, or intense physical activity , the body may not produce enough of them

Connexin43 (Cx43) is the most widely expressed connexin, and it is abundantly present on the apical protrusions of RMCs, which are involved in maintaining the vascular permeability of the retina and the structure of the BRB, as well as in regulating cell apoptosis ( 3.2.3 RMCs and growth factors Hyperglycemia promotes the secretion of growth factors, such as vascular endothelial growth factor (VEGF) (Schmalen et al., 2021), which are involved in the regulation of neovascularization and cause retinal fibrosis in DR

Brain 5 , 14 (2012)