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IMC also prevented diet-driven hepatic cholesterol accumulation and caused both upregulation of the host hepatic bile acid synthetic enzyme CYP7A1 and altered the expression of hepatic genes critical for bile acid feedback regulation

Because depression is a complex condition that often involves more than one root cause, its not unusual for patients to need multiple supportive treatments

J Med Chem 52 : 33773384

This study supports the use of targeted monoclonal antibodies to neutralize CD47 as a promising immunotherapeutic approach for resistant EGFR-mutant NSCLCs