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Description

Aldo Ammendola, Dimitri Abramov-Sommariva MD and Eugen Baumgaertner MD for critical discussions during the writing and reviewing process

Mayo et al

OCTN1 Transporter The operation of l-ergothioneine in organisms depends on a special transporter OCTN1 (organic cation transporter N1, product of the SLC22A4 gene), OCTN1 exists in keratinocytes and melanocytes and has a high affinity for ergothioneine, so skin tissue and cells can easily accept, absorb, and fully utilize l-ergothioneine