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Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material

Many experienced clinicians prefer to stack them because they address injury from two different angles

It inhibits the production of pro-inflammatory cytokines (TNF-alpha, IL-6, IL-12) and modulates macrophage polarization towards the M2 phenotype (reparative/anti-inflammatory)