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Tirzepatide also reduces liver fat, with studies showing meaningful improvements, but the magnitude does not approach what retatrutide achieves

HDLs primary receptor for cholesteryl ester (CE) uptake, scavenger receptor BI (SR-BI), is also a bidirectional free cholesterol transporter in that it facilitates the efflux and influx of free cholesterol between cells and mature HDL (693-695) (Figure 2)

All GLP-1 analogs suppressed Scd1 and Fasn gene expression in the liver, which are involved in lipid synthesis, was downregulated in all GLP-1 analog treatment groups (Fig

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